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Fluorose osseuse

La fluorose osseuse est une maladie osseuse causée par une quantité excessive de fluor dans les os[1].

Dents colorées par le fluor chez un patient vivant à Deming (Nouveau-Mexique) dans une zone connue pour ses fluoroses endémiques.

SymptĂ´mes

Le fluor peut entrainer des difformités osseuses : genu valgum, genu varum, ostéoporose, osteosclérose, ciphose[2] - [3] - [4] - [5] - [6].

Le fluor peut entrainer une attitude dite "poker back"[7] - [8], une impossibilité à effectuer un squat (position)[9], une respiration abdominale[9] et une capacité respiratoire réduite[10], de l'ostéoporose[10] - [11].

Articles connexes

Références
  1. « Glossaire: Fluorose osseuse », sur ec.europa.eu (consulté le )
  2. (en) « Genu Valgum Due to Fluoride Toxicity », Nutrition Reviews, vol. 33, no 3,‎ , p. 76–77 (ISSN 0029-6643, DOI 10.1111/j.1753-4887.1975.tb06023.x, lire en ligne, consulté le )
  3. « A STUDY ON CRIPPLING IN SKELETAL FLUOROSIS » : « Rigidity of Neck and Restricted Movements of Skull, Kyphosis of thoracic vertebrae, Scoliosis in the chest, bending downwards to see the floor without seeing the sky, criss cross walking, Joint pains in the upper and lower extremities, Genuvarum with bowing of leg, Crippling state of patient without movement, Paraesthesia and Paraplegia are the findings recorded crippling »
  4. « Endemic Fluorosis with Genu Valgum Syndrome in a Village of District Mandla, Madhya Pradesh »
  5. « A clinical and biochemical study of chronic fluoride toxicity in children of Kheru Thanda of Gulbarga district, Karnataka, India » : « Radiographic changes suggestive of osteoporosis, osteosclerosis, and genu valgum was observed. Major skeletal manifestations observed in various studies of fluorosis are bowed legs(genu varum) or knock-knee (genu valgum), and stiffness of the cervical andlumbar spine.Our study also revealed skeletal fluorosis with cripplingbone deformities »
  6. « Studies in Endemic Genu Valgum — A Manifestation of Fluoride Toxicity in India » : « The latter is characterized by the presence of genu valgum, dental fluorosis, osteosclerosis of the spine and simultaneous occurrence of osteoporosis of some other bones such as the lower limb bones. »
  7. (en) Jarrah Ali Al-Tubaikh, Internal Medicine : An Illustrated Radiological Guide, Springer, , 592 p. (ISBN 978-3-319-39747-4, lire en ligne), p. 154
    « An illustration demonstrates a patient with poker back due to fluorosis »
  8. (en) J. Luke, « Fluoride deposition in the aged human pineal gland », Caries Research, vol. 35,‎ , p. 125–128 (ISSN 0008-6568, PMID 11275672, DOI 10.1159/000047443, lire en ligne, consulté le ).
  9. « Endemic Fluorosis in the Madras Presidency »
  10. « Chronic fluorosis: The disease and its anaesthetic implications » : « Due to involvement of the rib cage, fluorosis causes restrictive lung disease with reduction in vital capacity and forced expiratory volume in 1 s/forced vital capacity ratios »
  11. « Fluoride’s Effects on the Formation of Teeth and Bones, and the Influence of Genetic » : « High systemic fluoride exposures can lead to skeletal fluorosis, a condition hallmarked by osteosclerosis, ligament calcifications, and often accompanying osteoporosis, osteomalacia, or osteopenia (Christie, 1980; Wang et al., 2007). »
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